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data from different cellular and molecular experimental platforms. Conducting studies in transgenic mouse models, managing mouse colony and their genotyping records. Develops and troubleshoots new
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, in vitro splicing and mouse models serve as systems in which to study the mechanism for alternative splicing as well as the biological endpoints of the pathways. The laboratory's approaches include
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, Biostatistics, Clinical Trials Office, Clinical Treatment Unit/Clinical Trials Processing Lab, Comparative Pathology and Mouse Phenotyping, Genetically Engineered Mouse Modeling, Genomics, Leukemia Tissue Bank
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and mechanisms of selective autophagy and lipid metabolisms in neural stem cells, microglia, and astrocytes. The lab developed novel genetically engineered mouse models to study roles of autophagy genes