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to develop new bioluminescent and other reporter strains of the multidrug-resistant human fungal pathogen Candida auris to support the development of murine infection models for antifungal efficacy
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seminars etc Supervise students on research related work and provide guidance to PhD students where appropriate to the discipline Contribute to developing new models, techniques and methods Undertake
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and Responsibilities: We are seeking a highly self-motivated postdoctoral candidate with experience in cancer research and strong analytical skills in single-cell RNA-seq data. Statistical modeling
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of the following projects: The molecular regulation of insulin secretion. In particular, the characterization of new (unpublished) transgenic models to study SENP1 (e.g. PMID: 38184650) The development of novel
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is currently employing multifaceted approaches and mouse disease models to uncover the novel immunostimulatory or immunosuppressive mechanisms of cGAS-STING pathway in antitumor immunity and
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biologists is expected. Much of the work will include utilization of human tissues and samples for in vitro work and modeling. In addition, some animal work may be involved. Qualifications Ph.D or M.D in
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: Strong research experience in functional genomics ( TALEN/CRISPR screening, FACS, next generation sequencing library preparation ) and patient iPSC-derived neuron/microglia/astrocyte models and brain
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efficacy in different animal tumor models leading to early phase clinical trials in pancreas, lung, and bladder tumor patients. The goal of these efforts is a start-up company utilizing GMP manufacturing
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preferred. Background with pharmacology, cell therapy or antibody engineering is also desired. · Previous experience in working with animal models of human cancers is preferred. · Literature
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role in developing our knowledge of the effect of radiation (microbeam +/- FLASH) on fibroblast and myeloid populations in pancreatic and bladder cancer models. About you The successful candidate must