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primary cardiomyocytes from human iPS cells, human myocardial slices from patients and humanised mouse models with the same mutations as patients, all of which are currently available in the laboratory
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, spatial, and social data into digital twin models for scenario testing and policy simulation. Adapt co-design methods to local contexts in demonstrator sites (Portugal, Sweden, Italy). Contribute to policy
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strategies, discovered within our group, to combat heart failure. The work will integrate studies using isolated cell systems with advanced in vivo models, with a particular focus on characterising newly
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on developing GaAs PICs in a project that includes everything from III-V laser epitaxy design and simulations, and fabrication, to system level PIC lidar tests and space qualification. Your role and goals You
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, such as sedimentation, meltwater flow, and vegetation change, into active drivers of adaptive design. This interdisciplinary work combines advanced computational tools, including 4D point cloud modeling and
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biopsies and in a newly developed swine ALS model. The postholder will lead wet-lab experimental work, across biophysical (MANT-ATP) and functional genomic assays (methylome, transcriptome and proteome
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individual muscle fibre, this project will determine the subtype-specific dysregulation of SkM in ALS, both in human patient biopsies and in a newly developed swine ALS model. The postholder will lead wet-lab
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interpretation of atmospheric circulation in high-resolution reanalysis data, idealised model simulations and a state-of-the-art weather forecasting system. The post-holder will have the opportunity to teach
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pipeline for cochlear tissue that is suitable to translate to our various mouse models we currently have running in the lab. There will also be good opportunity to collaborate with other members of the Nolan
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administering standardised or experimental assessments. Competence in data analysis and databased management, including techniques relevant to longitudinal studies (e.g. mixed models, SEM, in R, Stata, MPlus