- 
                
                
                tumour tissue and liquid biopsies for a comprehensive multi-omics characterisation and development of pre-clinical models of brain tumours. Collected snap-frozen tissue and liquid biopsies will be analysed 
- 
                
                
                of these cells in infection and cancer using murine models and human patient samples. The results will provide a step-change in our understanding of how memory T cell responses are controlled and reveal candidate 
- 
                
                
                of working with murine models, preferably models of neuroinflammation and / or neuro-oncology. Training will be available in all areas of the project. Experience performing intracranial surgery in mice would 
- 
                
                
                of Manchester and Oxford. The CoRE will leverage cutting edge computational approaches, novel experimental models, and experimental medicine studies to uncover how pollutants and infections interact with our