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–mediated antigen presentation in tumor cells, with the goal of increasing tumor visibility to cytotoxic immune cells. Candidates will have the opportunity to work with cutting-edge models and techniques in
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spectrometry-based metabolomics, isotope tracing, and lipidomics, to dissect metabolic rewiring in lung cancer. The research will integrate patient-derived models, organoids, and in vivo tumor models. Lab Focus
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-based modeling, and multi-omics analytics, including bulk, single-cell, and spatial transcriptomics, to uncover molecular mechanisms in cancer, immunology, and more. With a strong translational focus, the
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data from different cellular and molecular experimental platforms. Conducting studies in transgenic mouse models, managing mouse colony and their genotyping records. Develops and troubleshoots new
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, Biostatistics, Clinical Trials Office, Clinical Treatment Unit/Clinical Trials Processing Lab, Comparative Pathology and Mouse Phenotyping, Genetically Engineered Mouse Modeling, Genomics, Leukemia Tissue Bank
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and mechanisms of selective autophagy and lipid metabolisms in neural stem cells, microglia, and astrocytes. The lab developed novel genetically engineered mouse models to study roles of autophagy genes