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biofilm-related infections in orthopaedic implants: from in vitro to in vivo models Join the prestigious Marie Skłodowska-Curie Actions Doctoral Network SHIELD (Strategies for Healing Implant-associated
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through a combination of registry-based epidemiological studies, in vitro modelling of biofilm behaviour, and in vivo investigations of antibiotic pharmacokinetics and efficacy. The project is part of
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of implant surfaces functionalised with antimicrobial peptides (AMPs) using experimental infection models to assess the biocompatibility and therapeutic potential of AMP-coated titanium and polymers in
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and glycoproteomics. Computationally, they will engage in the analysis of various ‘omics data, be involved in using and improving AI models for glycan structure prediction, and perform biosynthetic
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develop and improve protein-glycan binding prediction models and use AI, data science, and bioinformatics to identify and design glycan-binding proteins with desired binding specificities. Qualifications
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in modulating bile duct inflammation and fibrosis using translational research models of PSC. This PhD project will employ a combination of in vitro (immortalized and primary cholangiocytes), ex vivo