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Great interest in pre-clinical in vivo models Ideally initial experience with Bioinformatics experience, especially in R What we offer Goal-oriented, individual training and development opportunities
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“Cellular Plasticity in Myeloid Malignancies: From Mechanisms to Therapies”. In this CRC we will focus on myeloid malignancies as a model to dissect the various molecular mechanisms that enable and regulate
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of the synthetic peptide in chronic and acute heart failure animal models. The therapeutic peptide is derived from the protein S100A1, which plays a central role in maintaining normal heart function. The synthetic
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, extension is sought) Contract:TV-L Your tasks Molecular laboratory work with 2D and 3D cell culture models Experimental design, data analysis and interpretation Publishing research findings in peer-reviewed
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against cardiac diseases. It is based on extensive preliminary work by our working group, which has demonstrated therapeutic effects of the synthetic peptide in chronic and acute heart failure animal models
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culturing, integrating multiple automated subsystems with image-based machine learning models. Our objective is to enable robotic decision-making through machine learning, paving the way for a standardized
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adults, characterised by severe genomic instability and a lack of targeted therapies. Using cutting-edge methods and unique primary patient-derived cell models, this project will seek to understand
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to generate reproducible, micrometer-scale controllable, and cost-efficient disease models by bringing together experts in molecular systems engineering, machine learning, biomedicine, and disease modeling
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-dimensional cell cultures are important to enable realistic cell environments for disease modeling and to analyze cell interactions. This position will address the question of how one can develop minimally
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of in vitro and in vivo pre-clinical models, including hiPSC-derived systems The postdoctoral project will combine experimental (wet-lab) and computational (dry lab) approaches Be part of Geman Center