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The Girardi Lab in the Department of Dermatology at Yale School of Medicine is seeking a Postdoctoral Associate to lead the development of next generation targeted antibody therapies for T cell
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invites applications for a postdoctoral position. The successful candidate will be driving cutting-edge research into the mechanisms and engineering of cell–cell fusion and cell signaling in human
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novel therapeutics. Responsibilities We are seeking a highly motivated and creative Postdoctoral Associate to join our team. The selected candidate will lead projects leveraging single-cell and spatial
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Lab to identify molecular signatures defining sickle cell disease (SCD) and reduced vaccine response by analysis of systems-level data profiling innate immunity and long-term adaptive immunity among
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regulatory mechanisms in mechanotransduction, aiming to understand how the regulation of mRNAs influences cell behavior in response to extracellular matrix and blood flow-induced hemodynamics. Ultimately, our
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, cellular and biochemical mechanisms that regulate innate immune cells and other pertinent intestinal cell subsets, particularly in the context of genetic variants associated with IBD susceptibility
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genomic pathology approaches, including CRISPR, single cell sequencing, spatial transcriptomics, and image analysis to address biologically- and clinically-driven questions. Our overall aim is to
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postdoctoral researcher will leverage state-of-the-art protein language models (PLMs) and advanced AI-based structural modeling techniques to design and optimize T and B cell receptors (TCRs and BCRs). The work
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skills (e.g. ranging from human subject consent, medical record abstraction, and processing human specimens), as well as cell biology techniques (e.g. DNA/RNA and protein extraction and quantification
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. Representative publications include: Mol Cell. 2024;84(3):463-475; Science. 2022;377(6612):1278-1285; Science. 2022;376(6600):1476-1481; Nature. 2021;598(7881):515-520; Molecular Cell. 2019;74(5):936-950; Science