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the normal processes of stem cell self-renewal and differentiation are regulated and how these processes are aberrantly regulated in hematological malignancies. The laboratory currently focuses on studying
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and in vivo models, including pancreatic islets. Develop and optimize cellular and animal models relevant to insulin resistance, beta-cell dysfunction, and related metabolic processes. Perform biomarker
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year of relevant experience Knowledge, Skills and Attitudes: Have graduate training or experience and background in experiences with utilizing animal models, cell line technology, and AAV or CRISPR
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. The successful candidate will integrate multi-omic and immunological approaches, such as single-cell transcriptomics, proteomics, and tumor microenvironment profiling, and apply bioinformatic tools (e.g., R
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, electrochemistry, and other tools for nanoparticle surface characterization to assess nanoparticle stability, chelation efficiency, and detoxification performance. Perform cell culture-based studies and other
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, genomics, or cell biology preferred. No prior experience required Skill in collecting, organizing, and analyzing data. Ability to recognize, analyze, and solve a variety of problems. Ability to exercise
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involving robotic platforms such as dual-arm manipulators, mobile robots, and wearable/exoskeleton robotic systems. Present research at national and international conferences and co-author peer-reviewed
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rely on mouse models (knockout mice, conditional knockout mice, transgenic mice, PDX mice) and primary cell culture and cell line models (2D/3D organoids). Applicants must be willing to work with mice
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mouse models of immune dysregulation and/or malignant hematopoiesis; Drug screening, flow cytometry and microscopy, CRISPR screening and human cell line models. Additional duties will include: Contribute
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cell RNA sequencing, chromatin conformation assays, and the integration of these approaches. The studies involved will have a focus on cancer and neurodegeneration genomics. The postdoctoral associate