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., Cancer Discovery, 2024; Luca, Steen et al., 2021, Cell), efforts to reveal biomarkers of in situ breast cancer progression (Strand et al., Cancer Cell, 2022; Risom et al. Cell, 2022), and response to PD-1
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(Siglecs) on immune cells to effect immunosuppression, akin to PDL1-PD1 interactions. In collaboration with Carolyn Bertozzi’s group, we are developing bifunctional proteins that include an antibody to cell
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Barone and Chris Lowe Stanford Departments and Centers: Biology Stem Cell Bio Regenerative Med Postdoc Appointment Term: 2-years Appointment Start Date: ASAP but flexible Group or Departmental Website
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genomics, and molecular biology techniques. Applicants with expertise and interest in (1) mass spectrometry-based proteomics, (2) molecular and cell biology including GPCRs, neuroscience, functional genomics
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will be focused primarily on the development and application of novel computational algorithms to analyze and integrate diverse omics datasets, including single-cell RNA-seq, spatial transcriptomics and
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in PAH. Our work blends classical cell and molecular biology with cutting-edge genomics and proteomics, aiming to identify novel therapeutic targets for PAH. Required Qualifications: Ideal candidates
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, proficiency in R and at least one additional scripting language (e.g., Python) and knowledge in biostatistics are required. Experience working with genetic association studies, immune repertoire, single cell
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to the in vivo study of retinal ganglion cell and astrocyte signal transduction. Current research in the Kapiloff lab addresses how calcium/calmodulin protein kinase II and cAMP signaling contribute
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of mechanosensitive ion channels in different cell types in the eye. Relevant techniques include 2 photon calcium imaging, retinal electrophysiology, rodent microsurgery and animal models of glaucoma and other ocular
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arterial hypertension using in vivo Perturb-seq. This project is related to a new NIH-funded Program Project Grant aimed at identifying differences and similarities in gene function across vascular cell