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mycobacterial infections. The student will characterise their mechanisms of action using cross-linking mass spectrometry and assess their effects on mycobacterial membrane integrity and cell wall metabolism
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-penetrating capabilities Evaluate delivery efficiency in cell-based models mimicking lung and immune tissues Identify structure–function relationships to inform rational design of future mucosal delivery
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. These mobile genetic elements autonomously transfer between bacteria, disseminating resistance genes across microbial populations. Recent advances have demonstrated the potential of “counter-plasmids” that can
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engineering and nano/microfabrication Materials characterisation techniques Microbiology and cell culture Translational research and clinical collaboration Regulatory considerations for medical devices
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Methods Soft lithography and microfabrication to create defined surface landscapes. • Mating assays between resistant and sensitive Enterobacteriaceae strains. • Live-cell imaging and fluorescent plasmid
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flow characterisation Nanoparticle synthesis and drug delivery systems Cell culturing and in vitro biofilm modelling Collaborative research across engineering, chemistry, dentistry, and microbiology
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single-component organic solar cell materials and how a temperature gradient is converted to electricity in organic thermoelectrics. An important aim of the simulations us to derive generally applicable