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immunotherapies in other diseases. The ideal candidate will have a strong background in cellular immunology and be proficient in analysing complex single-cell data. We utilise cutting-edge techniques, including
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approaches including targeted genetic murine models, primary cell culture and analysis, multi-omics and bioinformatics. The biological focus will be on vascular biology, immune cell function and metabolism
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Claudia Monaco’s research group at the Kennedy Institute of Rheumatology. In this role, you will apply single cell biology and cell signalling techniques combined with in vivo and in vitro models
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translational regulation, immuno-oncology and cancer genetics. The post involves working at the interface of computational informatics and cancer cell and molecular immunology. The post is funded by a
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strengths in laboratory-based enquiry using molecular genetics, metagenomics, biochemistry, cell biology, bioinformatics and structural biology, with rich clinical resources in microbiology, virology
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Brompton Hospital and Guy’s and St Thomas’ Hospitals. There will be opportunities for periods of secondment to the laboratories of collaborators, Professor Maddy Parsons (Randall Centre for Cell and
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environmentally relevant concentrations of CO influence: • Platelet activation and aggregation • Intracellular signalling pathways • Platelet-endothelial cell interactions The research has
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. There are four scientific Divisions - Structural Studies, Protein and Nucleic Acid Chemistry, Cell Biology and Neurobiology. However, scientific collaboration between the different Divisions is extensive
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cell RNA-seq, ATAC-seq Experience with python and/or R programming languages, including single cell package ecosystems (scanpy and/or Seurat) Experience working within HPC environments Experience working
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induced pluripotent stem cell (hiPSC) lines. The successful candidate will be responsible for generating brain organoids and assembloids, and to conducting a comprehensive analyses comparing wildtype and