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; Jacob et al., Cell Stem Cell 2022; Di Carlo et al., Nature Immunology 2023). Building on these findings, we aim at identifying novel mechanisms regulating the tumor microenvironment and antitumor immunity
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applications and in cell cultures. Organic synthesis and bioconjugation. Absorbance and fluorescence spectroscopy. Biophysical studies (FIDA, BLI, ITC, NMR). Cell culture, fluorescence microscopy, flow cytometry
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and identification of proteins associated with viral genomes in different cell models (human, rodent, avian, snake and insect). - CRISPR and RNAi genetic screens - Viral production and infection in L-3
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media in order to identify predictive markers. Of note, we are focusing on human embryos since results clearly show that molecular differences with mouse or stem cell models call for more work on human
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fundamental in cell biology, complementing membrane-bound organelles in the organization of cellular functions. Biomolecular condensates are mesoscopic membrane-less organelles that allow the dynamic
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with a strong synthesis of molecular and cellular biology, single-cell physics, microfluidics and mathematics. From this joint point of view, it is very promising to treat a phenotype as a product of
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: Rheometry, with a measurement cell allowing controlled mass transfer (ions / enzymes), in order to establish the relationships between chemical reactions and the dynamic evolution of the gel's rheological
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Description The University of Technology of Compiègne is recruiting a contract researcher for the Heudiasyc Laboratory (UMR CNRS 7253), Department of Computer Engineering (GI). The project aims to equip mobile
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. The successful candidate will play a key role in the instrumentation and control of mobile robots (rolling and/or flying) endowed with resilient structures and proprioception. Project context The ResiRob project
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currently being developed in the laboratory (TRL3 to TRL5), (ii) manufacturing the new version of the device in a clean room and (iii) testing it in cell culture laboratory to define the efficacy of new