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dynamic research community. Research in the Alexander Lab spans scales of biology as well as experimental and computational approaches. The ideal candidate will have a strong interest in gene regulatory
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hematopoietic cell development and hematologic cancers. Based on these basic mechanistic insights, the Laboratory is building innovative therapeutics to treat hematopoietic cancers that are currently without
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massively parallel reporter assays (MPRAs) and CRISPR interference (CRISPRi), to investigate the regulatory genomic elements (enhancers and promoters) that control gene expression across various cell types
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organ 3D imaging at single cell resolution of the disease (PMID 34788609). This now allows them to map and functionally probe the neuro-metastatic interface (reviewed in 32302564). The work is a close