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The Girardi Lab in the Department of Dermatology at Yale School of Medicine is seeking a Postdoctoral Associate to lead the development of next generation targeted antibody therapies for T cell
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: protein biochemistry, cell biology, structural biology, protein engineering, antibody discovery, reproductive biology, and immunology. The successful candidate will receive the scientific, communication
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novel therapeutics. Responsibilities We are seeking a highly motivated and creative Postdoctoral Associate to join our team. The selected candidate will lead projects leveraging single-cell and spatial
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Lab to identify molecular signatures defining sickle cell disease (SCD) and reduced vaccine response by analysis of systems-level data profiling innate immunity and long-term adaptive immunity among
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genomic pathology approaches, including CRISPR, single cell sequencing, spatial transcriptomics, and image analysis to address biologically- and clinically-driven questions. Our overall aim is to
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postdoctoral researcher will leverage state-of-the-art protein language models (PLMs) and advanced AI-based structural modeling techniques to design and optimize T and B cell receptors (TCRs and BCRs). The work
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the cell intrinsic immune machinery and DNA damage and repair processes using in vitro cell models, genetic screens (such as CRISPR and RNA interference), and animal models. We have a strong translational
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Oncology, 2022; McFall T et al, Cell Communication and Signaling, 2021; Kato and McFall et al, The Oncologist, 2021). The lab is prepared to make a similar investment of time and resources to help a highly
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methylation sequencing, single cell DNA methylation, and single cell transcriptome • Perform machine learning/deep learning analyses; and delivering analytical results. • Develop workflows for multiple
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analyse complex data from emerging genomic pathology approaches, including CRISPR, single cell sequencing, spatial transcriptomics, and image analysis to address biologically- and clinically-driven