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PhD Studentship: Dissecting the Molecular Architecture and Function of LMTK3 as a Therapeutic Target
; University of Sussex | The City of Brighton and Hove, England | United Kingdom | about 1 month agomechanisms underpinning LMTK3's multifaceted role in cancer biology. By employing a multidisciplinary approach combining structural biology, biochemistry, and cell biology, this research aims to provide novel
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and synthesis of new materials. For the DED-LB additive manufacturing, the lab has a house-developed Laser-Kuka cell with a 16kW IPG laser and wire/powder feeding systems. The lead supervisor, Dr Yuze
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, with experience in contemporary molecular cell biology, tumour metabolism, experimental modelling and bioinformatics as applied to translational cancer genomics, ideally within the context of childhood
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and stem cell biology. The study investigates how APOE4 expression in endothelial cells affects oligodendrocyte progenitor cells (OPCs), using iPSC-derived 3D co-culture models. This work aims to
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. cell culture, molecular biology, imaging, cell signalling assays). As well as performing experiments on the project, the role will involve providing training in techniques to relevant staff/students
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reading and writing skills; good at understanding and explaining concepts Knowledge of on electric vehicle fuel cell systems and CAN communication protocol. Possesses strong problem solving skills
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to understand behaviour through the lens of digital footprint/“smart data” datasets, cutting across sectors ranging through health, retail, mobility, energy and communications. Using GI infections as a case study
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experience in microfabrication techniques and knowledge of basic mechanics and electronics. Candidates should demonstrate strong communication skills, self-motivation, and a commitment to collaborative
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hepatic dysfunction in Alpers’ syndrome. The proposed studentship will involve a multi-disciplinary mechanistic approach harnessing induced pluripotent stem cell (iPSC) in vitro models and a unique resource
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or equivalent) for candidates for whom English is not their first language is required. Our research environment is enriched by the diversity of our staff and students and we take a responsible approach towards