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mutant and transgenic reporter lines in zebrafish and mouse Participate in all the metabolomic and singe cell transcriptomic aspects of the study, from sample preparation to data analysis Perform
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of brain and other mouse tissues.•Animal experimentation, including injections, perfusion, etc.•Molecular and cellular biology experimentation (e.g., PCR, Immunoblotting, cell culture)•Maintenance
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Pasteur and aims at understanding hearing from both a fundamental and clinical perspective. It combines various approaches from genetics and cell biology to biophysics and from human cognition and
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of β-1,6-glucan, a cell wall polymer, and is part of a multidisciplinary consortium comprising to other teams: Sarah Wong (Immunology of Fungal Infections, Institut Pasteur) and Lionel Ballut (Institut
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with existing single-cell methods and software would represent a strong advantage. Excellent communication skills and team spirit, and an ability to work in autonomy are essential. Fluent English both
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, England P, Gielen M, et al. ‘An Original Potentiating Mechanism Revealed by the Cryo-EM Structures of the Human Α7 Nicotinic Receptor in Complex with Nanobodies’. Nature Communications 14, no. 1 (25
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organismal properties encoded in the interplay of multiple genes in a network? How does the polymer physics at the level of the DNA affect the identity of a particular cell type? Alternative questions
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autism and neurodevelopmental disorders based on database review. Mol. Cell. Neurosci. 2021 Jun;113:103623. Leblond C.S. et al. Both rare and common genetic variants contribute to autism in the Faroe