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delivery systems (ODDs) that adopt a more proactive approach to disease treatment, by targeting endogenous pathways involved in cellular longevity and mitochondrial function before the development of severe
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oxidative stress and mitochondrial function assays which include measuring reactive oxygen species and mitochondrial bioenergetics. f. Simulating microgravity conditions to study physiological responses. g
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response, specifically focusing on mitochondrial stress, endoplasmic reticulum (ER) stress, and downstream integrated stress response (ISR). We employ an interdisciplinary approach, integrating structural
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, based in the Department of Anatomy and Neuroscience at University College Cork, investigates the cellular and mitochondrial mechanisms that regulate dopaminergic neuron vulnerability in ageing and
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Biochemistry Research Assistants 01 Department's Website: Summary of Job Duties: The Postdoctoral Fellow will conduct independent and collaborative research on mitochondrial membrane proteins. The position
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on molecular methods, which represent a more reliable alternative tools for a correct species identification. The use of molecular markers, such as mitochondrial genes, ribosomal genes, or microsatellites, will
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neurodevelopmental, neuropsychiatric, or neurodegenerative disorders, with particular emphasis on the role of mitochondrial dysfunction and metabolic deficits in disease progression. To address these questions, we use
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Experience: Established record of scholarly productivity in basic, translational, or clinical geroscience research, particularly in areas such as epigenetics, mitochondrial function, metabolism, inflammaging
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real-time PCR is required. Previous experience/knowledge in animal experiments is much preferred, and experience in cardiology and mitochondrial physiology research is a plus. In addition, capabilities
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include e.g. data quality controls, mapping of DNA data to reference genomes, investigation of deamination patterns, analysis of sex chromosomes, analysis of mitochondrial and Y-chromosome haplogroups