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). mTORC1 Regulates Mitochondrial Integrated Stress Response and Mitochondrial Myopathy Progression. Cell Metabolism 26, 419-428 e415. We are located in a modern research hub called NEO at Karolinska
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that result in neurodevelopmental, neuropsychiatric, or neurodegenerative disorders, with particular emphasis on the role of mitochondrial dysfunction and metabolic deficits in disease progression. To address
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position within a Research Infrastructure? No Offer Description Laboratory of RNA Biology IBB PAS seeks a highly motivated Postdoc candidate who would like to join a mitochondrial research group working
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position within a Research Infrastructure? No Offer Description Laboratory of RNA Biology IBB PAS seeks a highly motivated Postdoc candidate who would like to join a mitochondrial research group working
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University of Massachusetts Medical School | Worcester, Massachusetts | United States | about 2 months ago
for neurological and mitochondrial diseases. Our active research projects include: Gene editing in mitochondrial DNA: we use base editing technologies to create mouse models for gene mutations in the mitochondrial
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in peripheral neuropathy. In particular, we are interested in the unique metabolic vulnerability of motor axons and how metabolic deficits and mitochondrial dysfunction in Schwann cells contribute
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assays (IC50), and mechanism of action tests (PCR, cell cycle analysis, apoptosis/necrosis detection, GSH levels, mitochondrial membrane potential, AP sites); • experience in analyzing results
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mutations, mitochondrial dysfunction and chronic inflammation intersect to contribute to clinical and pathological heterogeneity in PD. The successful candidate will work at the interface of basic and
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laboratory to elucidate the effect of Abeta42 on mitochondrial liquid-liquid phase separation using live-imaging techniques. Research activities will focus on: (1) Molecular mechanism of amyotrophic lateral
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mitochondrial preparation by the project's partner team at the University of Toulouse). The candidate will be hosted within the team “Structural Flexibility of Biomolecules in Complex Environments” at the BIP