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of the MiRMet project are to mechanistically decipher how dysfunctional mitochondria are recognized and targeted for lysosomal destruction under hypoxic and OXPHOS conditions and to characterize the role
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under the supervision of Dr Roman Szczesny. Mitochondria are essential organelles found in almost all eukaryotic cells. Due to the organization of human mitochondrial DNA, the regulation of individual
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The International Institute of Molecular Mechanisms and Machines Polish Academy of Sciences | Poland | 16 days ago
Institute of Molecular Mechanisms and Machines, (IMOL), Poland, Leicester Institute of Structural and Chemical Biology, United Kingdom. SubProject: Structural mechanisms of protein transport into mitochondria
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The International Institute of Molecular Mechanisms and Machines Polish Academy of Sciences | Poland | about 1 month ago
Chacinska Group (https://imol.institute/leaders/chacinska-group/ ) Project title: “Role of interaction of the TOM translocase with BAG2 and TRABD proteins in the proteostasis of mitochondria” Download
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pyruvate kinase M2 maintains vascular integrity (Kim et al. JCI, 2018): https://www.jci.org/articles/view/120912 HIF2α inhibits glutaminase clustering in mitochondria to sustain growth of clear cell renal
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to damage, with a primary focus on the endolysosomal system and mitochondria? What are the protein interaction networks that make up dynamic organelles? How to familial mutations in key organellar systems
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The International Institute of Molecular Mechanisms and Machines Polish Academy of Sciences | Poland | about 1 month ago
(https://imol.institute/leaders/chacinska-group/ ) Project title: “Role of interaction of the TOM translocase with BAG2 and TRABD proteins in the proteostasis of mitochondria” Download the description
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The International Institute of Molecular Mechanisms and Machines Polish Academy of Sciences | Poland | about 1 month ago
-group/ ) Project title: “Regulation of Protein Import into Human Mitochondria and its Impact on the Mitochondrial Proteome” Download the description of the project: https://ncn.gov.pl/sites/default/files
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The International Institute of Molecular Mechanisms and Machines Polish Academy of Sciences | Poland | about 1 month ago
/ ) Project title: Regulation of Protein Import into Human Mitochondria and its Impact on the Mitochondrial Proteome Download the description of the project: https://ncn.gov.pl/sites/default/files/listy
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unique intracellular symbiont capable of invading mitochondria of oocytes of several tick species, e.g. Ixodes ricinus. Despite its exceptional biology, the mechanisms underlying mitochondrial specificity