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(microglia and border-associated macrophages) interacts with glia (astrocytes) to influence neuronal synapses, as well as peripheral immune contributions such as gut-brain signaling. Our interdisciplinary work
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-pluripotent stem cells (iPSC), perform immunofluorescence experiments, and help with the analysis of scRNAseq data. They will perform differentiation protocols for generation of microglia and microglia-organoid
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Description The laboratory of Microglia and Inflammation in Neurological Diseases (MIND), headed by Renzo Mancuso, is a part of the VIB-Center for Molecular Neurology (CMN) and focuses on multiple
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). Immunohistochemistry to analyze the content of tyrosine hydroxylase and alpha-synuclein, neuronal death and activation of microglia and astrocytes, in the striatum and substantia nigra. Analysis of the content of GABAA
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-generation humanized models for studying peripheral neuroimmunity in Parkinson’s disease The Laboratories for Gut-Immune-Brain Axis Research (GIBA, Prof. Seppe De Schepper) and the Microglia and Inflammation
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behavior or microglia. The applicant should have publication(s) in related fields. The applicant should have communication skills. Website for additional job details https://emploi.cnrs.fr/Offres/CDD/UMR8265
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medical treatments (https://www.stemcells.cam.ac.uk/ ). The laboratory of Prof. Thóra Káradóttir (https://www.stemcells.cam.ac.uk/people/pi/karadottir ) uses multidisciplinary approaches to investigate
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to study the roles of microglia and oligodendrocytes in neurodegeneration and cognitive function. Analyze high-dimensional data to identify molecular pathways and targets relevant to Alzheimer’s disease and
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have hands-on experience working with immune-related cell types, particularly microglia or macrophages. A strong command of written and spoken English is required. Applications should be addressed to Dr
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, genetic, and transcriptomic analyses of key regulators of brain aging using mouse and cerebral organoid models. Design and perform experiments to study the roles of microglia and oligodendrocytes in