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the extracellular space remains unclear. In this project, the interdisciplinary team will combine their expertise in bio-microfluidics (Thomas Pfohl, Physics Institute, University of Freiburg), bacterial ECM
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quantitative image analysis, numerical modeling, and explainable AI (XAI) with state-of-the-art biophysical methods. Using techniques such as traction force microscopy, microfluidics, 3D bioprinting, and
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laser diffractometry and fluorescence microscopy • Investigate bacteria on a single-cell level using microfluidics and flow-cytometry • Quantify the production of amino acids and metabolic fluxes via mass
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laser diffractometry and fluorescence microscopy • Investigate bacteria on a single-cell level using microfluidics and flow-cytometry • Quantify the production of amino acids and metabolic fluxes via mass
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of specialized microfluidic chip systems using two-photon micro-manufacturing, and examine the delivery of chemotherapeutic agents through these systems. Expected Results Functional 3D bioprinted in-vitro
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biophysical measurements (atomic force microscopy, microfluidics, molecular tweezers, and other techniques adapted to the study of nuclear mechanical properties). Candidate Profile The candidate should have a
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of precision fermentation or cell culture - Affinity towards technical tasks and bioprocess control - Advantageous: Experience in mathematic modeling, programming, CAD, microfluidic or bioreactor systems
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), IBPS, Sorbonne Université. The team possesses expertise in developing application-specific microfluidic models that integrate desired mechanical conditions of fluid flow and substrate viscoelasticity
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using biochemical and biophysical methods. Bridging protein-level approaches (mutagenesis, immobilization, expression optimization) with process-level solutions (bubble columns, microfluidic devices
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screening (microfluidics) to discover new enzymes and bioactive molecules with applications in biotechnology, medicine, and sustainability. The network brings together leading academic and industrial partners