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the extracellular space remains unclear. In this project, the interdisciplinary team will combine their expertise in bio-microfluidics (Thomas Pfohl, Physics Institute, University of Freiburg), bacterial ECM
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quantitative image analysis, numerical modeling, and explainable AI (XAI) with state-of-the-art biophysical methods. Using techniques such as traction force microscopy, microfluidics, 3D bioprinting, and
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laser diffractometry and fluorescence microscopy • Investigate bacteria on a single-cell level using microfluidics and flow-cytometry • Quantify the production of amino acids and metabolic fluxes via mass
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laser diffractometry and fluorescence microscopy • Investigate bacteria on a single-cell level using microfluidics and flow-cytometry • Quantify the production of amino acids and metabolic fluxes via mass
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of precision fermentation or cell culture - Affinity towards technical tasks and bioprocess control - Advantageous: Experience in mathematic modeling, programming, CAD, microfluidic or bioreactor systems
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), IBPS, Sorbonne Université. The team possesses expertise in developing application-specific microfluidic models that integrate desired mechanical conditions of fluid flow and substrate viscoelasticity
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using biochemical and biophysical methods. Bridging protein-level approaches (mutagenesis, immobilization, expression optimization) with process-level solutions (bubble columns, microfluidic devices
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-cultures, the system will enable real-time investigation of how mechanical stimulation affects inflammation, matrix organisation, and tissue repair. The project will involve microfluidic design, 3D
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, biosensing, microfluidic mixing, or self-healing materials. The successful candidate will join the Active Soft Matter Lab within the TNW Faculty, the MESA+ Institute for Nanotechnology, University of Twente
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and microfluidics to overcome perfusion limitations in thick tissues. Project Goal 1: Define and produce a printable hydrogel system to produce high resolution scaffolds with cell guidance properties