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Methods Soft lithography and microfabrication to create defined surface landscapes. • Mating assays between resistant and sensitive Enterobacteriaceae strains. • Live-cell imaging and fluorescent plasmid
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culture and in vitro models of mucosal immunity Data analysis using Python and digital image processing These skills are highly transferable to careers in biomedical research, pharmaceutical development
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Microfluidics and lateral flow assay engineering Translational diagnostics and AMR-focused assay development Digital image analysis and Python-based data processing The project includes opportunities
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Student Development The successful applicant will gain expertise in: Biophysical imaging (AFM, microscopy) Microbiology and molecular biology RNA sequencing and data analysis Interdisciplinary collaboration
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Abstract: Medical device-associated infections (MDAIs) are a major clinical and economic burden, particularly in orthopaedics where implant-related infections can lead to severe complications, including
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disinfectants. With antimicrobial resistance (AMR) on the rise, there is an urgent need for non-antibiotic strategies to prevent and control biofilm formation on medical devices. This PhD project proposes a novel
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, and processing conditions influence their behaviour, creating a vast and complex landscape that traditional experimentation cannot navigate efficiently. This project addresses this challenge by bringing
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Abstract: Tuberculosis (TB), caused by Mycobacterium tuberculosis, remains a leading contributor to global antimicrobial resistance (AMR). Non-tuberculous mycobacteria (NTM) also pose serious threats, particularly to immunocompromised individuals. This project investigates two underexplored...
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Supervisors: Prof Stavroula Balabani Prof Panagiota Angeli Abstract: Oral biofilms are a major cause of dental and periodontal diseases, including endodontic infections and dental caries the most prevalent noncommunicable disease globally. The confined and complex architecture of the oral...
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at scale. Training and Student Development: The student will gain interdisciplinary training in: Advanced molecular cloning, CRISPR-Cas systems, and genome engineering Bioreactor operation and process