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PhD candidate in Design and synthesis of pyrophosphate mimetics to study enzymes involved in natural
by ADP-ribosyltransferases of the PARP family, while ADP-ribosylhydrolases remove the ADP-ribose residue. Understanding the detailed mechanisms of such modification and demodification is vital
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match the chemical, mechanical, and morphological properties of native bone. The role of the PhD student at Empa will be the development of synthesis processes using light-based 3D printing of hydrogel
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Award summary 100% of home tuition fees paid and an annual stipend (living expenses) of £20,780 Overview Interested in developing new experimental systems for previously unknown disease mechanisms
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to mechanical forces. We work with leading international groups on modeling and also conduct simulations at DTU. Our overarching goal is to understand and predict the mechanical behavior of metals during plastic
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, this interdisciplinary project will focus on developing robust, practical tools to assess and predict recyclate quality. The work will involve thermal analysis (e.g. DSC, TGA), rheology, mechanical testing, and molecular
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: From Mechanisms to Therapies”. In this CRC we aim to understand how plasticity i.e. non-genetic adaptations of the bone marrow niche induced by the disease or therapeutic agents contribute to drug
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energy through more efficient design of piled foundations. The PhD student will focus on grain scale mechanics experiments and numerical modelling using the Discrete Element Method (DEM) with the aim
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sequencing, bulk and single-cell RNA-seq. These methodologies will be refined and later applied to Welsh genomic resources (SAIL/AWMGS) to identify patient subgroups, uncover disease-driving mechanisms, and
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integration and plasticity at spinal nociceptive synapses, with particular emphasis on sex-specific mechanisms and glial adaptations that may influence the transition from acute to chronic pain, as well as its
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couplings enable self-alignment purely through geometry and contact mechanics, offering a fast, robust, and repeatable solution for high-tech applications. Although the concept of kinematic couplings has