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strategic directions for innovation-driven impact. Finally, the researcher will lead an investigation on the opportunities to develop a science-based, robust mechanism of testing and validating innovative
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techniques such as western blotting, flow cytometry, fluorescence microscopy, and/or molecular cloning. The project aims to determine the molecular mechanisms underlying a rare genetic disorder called Rothmund
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immunomodulation and therapy resistance in prostate cancer. This project, part of a FAPESP Thematic Grant, aims to uncover molecular mechanisms driving immune evasion and identify combinatorial therapeutic
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the genetic and biological mechanisms that drive metastasis and treatment resistance. The fellow will isolate CTCs, establish patient-matched organoids from both CTCs and primary tumors, and perform comparative
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Paulo (ICB/USP) to work in the FAPESP-Thematic Project “Neurodegenerative Diseases Associated with Aging: From the Cell to the Patient.” The project aims to elucidate the neural mechanisms linking
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to elucidate cellular and molecular mechanisms underlying DMD and healthy aging, employing iPSC-derived cellular models, skeletal muscle differentiation, and three-dimensional muscle tissue engineering
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techniques will be employed to dissect the mechanisms of recruitment of T6SS effectors to the T6SS machinery. Candidates should have experience in molecular biology techniques, protein biochemistry, structural
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genetics and cell biology applied to Duchenne Muscular Dystrophy (DMD) and aging, using induced pluripotent stem cells (iPSCs). The project aims to elucidate cellular and molecular mechanisms underlying DMD
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, with a view to circular economy. The scholarship recipient will be responsible for further investigating the interaction mechanisms involved during the sorption and desorption process, evaluating
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real scenarios; 3. Manufacture and test prototypes of optimized end plates using additive manufacturing, experimentally validating their mechanical, thermal, and electrochemical performance under