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Primary supervisor - Dr Myriam Charpentier Nitrogen (N) acquisition is fundamental for plant growth. However, N is poorly available in soils, leading to extensive and costly chemical fertiliser applications. It is estimated that 50-70% of nitrogen-derived fertilizer provided to the soil is lost,...
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, offers new opportunities to protecting crops and securing high yielding harvests in a sustainable way. A key component of plants’ immune systems are intracellular receptors that detect the presence
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mechanisms of the sexual conflict and its resolution. You will combine cutting-edge bioinformatics, genome engineering, and state-of-the-art sequencing technologies to: Identify and characterise consistent
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plants. To better understand how distantly-related land plants defend themselves against pathogen infection, our group investigates the molecular genetic mechanisms controlling disease resistance in
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to regulate lipid metabolism in hepatocytes and its impairment contributes to fatty liver. Importantly, the role of alternative cellular mechanisms of intracellular cargo degradation like LC3-associated
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these and/or other potential mechanisms to establish whether individual bacteria can initiate specific cancer-causing mechanisms. The project is linked to work carried out as part of the Pan Prostate Cancer
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communicate with beneficial soil microbes to enhance nutrient uptake and resilience. This project aims to uncover key molecular calcium signalling mechanisms at the heart of plant-endosymbiont partnerships
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the mechanisms associated with loss of virulence, as well as identifying novel genetic determinants of pathogenicity. The project will provide broad training in molecular genetics, genomics, cell biology, and
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scope to adapt some elements of the PhD to their interests. There will also be opportunities to join related project teams in long-term condiWe are seeking a motivated and compassionate student with a
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) Determining its involvement in pathways that promote healthy ageing In addition, we will collaborate with the lab of Prof. Tom Wileman to determine the conservation of these mechanisms in mammalian cells