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that restore immune function could therefore have substantial therapeutic applications. Cellular metabolism is an important mechanism regulating immune function. This PhD project will use a combination of
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therefore have substantial therapeutic applications. Cellular metabolism is an important mechanism regulating immune function. This PhD project will use a combination of synthetic chemistry, proteomics, and
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PhD candidate in Design and synthesis of pyrophosphate mimetics to study enzymes involved in natural
by ADP-ribosyltransferases of the PARP family, while ADP-ribosylhydrolases remove the ADP-ribose residue. Understanding the detailed mechanisms of such modification and demodification is vital
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. Diversity and inclusion Fostering an inclusive community is a central element of the values and vision of Leiden University. Leiden University is committed to becoming an inclusive community which enables all