15 mechanics-finite-element PhD positions at University of Cambridge in United Kingdom
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studies of a shortlist of identified targets. These studies may uncover mechanisms of cellular responses, potential biomarkers and additional therapeutic vulnerabilities that underlie the responses
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earlier as well as understand the mechanisms driving CIN. This project will aim to build upon previous work within the group developing computational methodologies to detect and deconvolute the mutational
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, Su J, Eldridge MD, Riedel A, Serrao E, Rodewald HR, Mack M, Shields J, Cohen ES, McKenzie ANJ, Goodwin RJA, Brindle K, Marioni JC, Halim TY. (2020) ILC2-driven innate immune checkpoint mechanism
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for matching novel protein targets with their optimal expression conditions. Altogether, this project will provide new insights into the mechanisms limiting expression of challenging proteins and how
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technologies, bulk and single-cell RNA-sequencing, flow cytometry, multiplex immunofluorescence, and standard molecular biology and biochemistry techniques. A computational component may also be available