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to decipher the regulatory code controlling gene expression in plants through the engineering and large-scale validation of synthetic promoters. Within the ERC-funded multiCODE project, we aim
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scientist to study the human-specific genetic mechanisms of development and function of cortical neurons. Join us to undertake a highly interdisciplinary project focusing on a long-standing and fascinating
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. At our Center, researchers study the cellular mechanisms of health and disease in the central nervous system. The De Wit lab (Laboratory of Synapse Biology) at the VIB-KU Leuven Center for Brain & Disease
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. The impact of microglia during the progression of neuropathology is dictated by their subtype composition – as different subsets will lead to different functional outcomes. Microglia transcriptional
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that mimick human striatal function and we are using these systems to study the mechanisms of Parkinson’s disease. The system, that involves a high density multielectrode array enables us to measure single
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Postdoctoral position to study species-specific mechanisms of gene regulation in human neurons. The Vanderhaeghen Lab (https://pvdhlab.org ) and the Aerts Lab (www.aertslab.org ) at VIB KULeuven
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for months, years, or even millennia. Our lab aims to resolve the molecular mechanisms behind this process, focusing on how promiscuous enzymes (un)intentionally transform cellular metabolites into degradation
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. The impact of microglia during the progression of neuropathology is dictated by their subtype composition – as different subsets will lead to different functional outcomes. Microglia transcriptional
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metastasis and novel metabolic pathways. We exploit mouse models, genetic engineering, metabolomics and single cell & spatial multi-omics analysis to gain groundbreaking insights into metabolism as a driving
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record in exploring urology‑relevant sensory mechanisms, with translational relevance for conditions such as chronic pain, bladder dysfunction, and other urinary tract disorders. The urinary bladder plays