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Institute of Biomedicine, Sahlgrenska Academy, University of Gothenburg | Sweden | about 11 hours ago
structural biology, high-resolution mass spectrometry, and advanced bioinformatic approaches—are urgently needed. The primary aim of this PhD project is to advance the clinical diagnostics of infectious
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connections with laboratory specialists, researchers, and clinicians. The Functional Genomics subteam develops mass‑spectrometry‑based proteomics, glycoproteomics, and metabolomics methodologies
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connections with laboratory specialists, researchers, and clinicians. The Functional Genomics subteam develops mass‑spectrometry‑based proteomics, glycoproteomics, and metabolomics methodologies
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polymerization and electropolymerization. The structures will be confirmed, for example, by 1H and 13C NMR titration, FTIR, mass spectrometry, UV-vis and fluorescence spectroscopy, electrochemistry, size exclusion
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Main description: Native mass spectrometry is an expanding structural biology tool to elucidate the function of protein complexes. Excitingly, the demand for this technology is increasing. However
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affinity-coupled mass-spectrometry to determine the impact of chaperone protein variants on protein interactions, characterizing cardiac development in zebrafish expressing chaperone protein variants, and
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collaborations. You would have direct access to state-of-the-art cell and molecular biology facilities, mouse and chicken chorioallantoic membrane (CAM) modeling platforms, mass-spectrometry, next-generation
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on developing new methods and applications of metabolite profiling using a combination of mass spectrometry (MS) and NMR platforms which provide a broad-based approach for biomarker discovery and systems biology
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and Responsibilities: Develop mass spectrometry and proteomics approaches and characterize novel affinity-binders for detection and quantification of post-translational modifications in proteins and
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-on experience on (ultra) high-performance liquid chromatography hyphenated to high-resolution mass spectrometry; and c) proficiency in the utilization of specific software’s for data processing and interpretation