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the individual ubiquitin moieties, such chains can adopt many distinct geometries and - by means of linkage-selective downstream effectors - convey distinct biological effects. In this manner, the ubiquitin system
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that many different RNA modifications exist. Yet, the true dimensions of the epitranscriptome were unveiled only in the last decade. It is now evident that RNA modifications affect the stability, function
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benefits: 232 holiday hours per year (based on full-time) and extra holidays between Christmas and 1 January; multiple courses to follow from our Teaching and Learning Centre; a complete educational program
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in early zebrafish embryos. Many of these proteins are established translational repressors, but intriguingly, I discovered links between storage granule components and the translation machinery. In
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: In higher eukaryotes, proteins that lack an apparent folded structure are enriched in many vital processes. The Lemke group studies intrinsically disordered proteins in vital cellular processes
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. We are looking for PhD students to join the Hermans Lab and take the next step and build a next-generation quantum network. Can we control multiple of these REIs within the same chip and perform two
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finger, this simple approximation enables the practitioner to determine the quantity of applied drug substance onto the skin. These simple logical steps transformed clinical practice and today the FTU
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-generation quantum network. Can we control multiple of these REIs within the same chip and perform two-qubit gates between them? Using such coupled emitters, is it possible to run advanced entanglement
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. Many histone modifications leave long-term epigenetic memory in cells and can be transmitted across generations, raising the possibility that DNA damage can reshape the epigenome in damaged cells and
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. Epitranscriptomics is a new science field that studies RNA modifications (epitranscriptomic marks) and their function in regulation of gene expression. It is long known that many different RNA modifications exist. Yet