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. Computational and bioinformatic skills. Experience in microscopy. Generation and analysis of mouse models. Handling of human samples. Molecular biology skills including CRISPR, cloning and qPCR. In vitro cell
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Position Summary A Mathematical Epidemiology/Infectious Disease Modeling position is available in the Mitreva Lab with the Division of Infectious Diseases, Department of Medicine and McDonnell
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implement algorithms, models, and software applications that can be translated to clinical use. Job Description Primary Duties & Responsibilities: Information on being a postdoc at WashU in St. Louis can be
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Science 371:1154). The position will involve utilizing human specimens, cell culture models (epithelial and immune cells) and testing hypothesis in mouse models of the disease. Appropriate training in all
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dementias. We use a combination of iPSC-based systems and transgenic mouse models coupled with novel approaches including single-cell sequencing, CRISPR–Cas9 screening, and interactome profiling. The work
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. Working experience with mouse models of cancer. Experience with software such as ImageJ, Microsoft Office, and GraphPad Prism. Preferred Qualifications Education: No additional education unless stated
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, (2) dissecting the pathways and mechanisms that may underlie changes in cell states such as partial epithelial-to-mesenchymal transition, and (3) establishing novel model of human tumors (e.g., PDX
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. The successful candidate will be a member of a highly interdisciplinary team including oncologists, biologists, engineers, and imaging scientists. The candidate will develop computational models of human disease
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approach, spanning basic biology and translational medicine using mouse models and patient samples, tackles complex questions with profound implications for human health. Projects are available to decipher
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, to define novel biomarkers, and to identify novel therapeutical targets. We have pioneered in the integration of genetics with omic data to identify proteomic signatures and develop novel predictive models