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Saelens team. Research Project In this research project you will develop probabilistic deep-learning models that automatically extract biological and statistical knowledge from in vivo perturbational omics
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neuroinflammation. The PhD student will focus on characterizing immune cell responses in food allergy models and their impact on brain immunity. In close collaboration with experts in food allergy, neuroimmunology
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and Saeys teams. In this research project you will develop and apply algorithms to link clinical phenotypes of metastasis to molecular phenotypes in mouse models. It is known that metastases exhibit
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or altered behavioral responses in ASD models How these changes reflect underlying shifts in cortical circuit function You will work within the Bonin and Farrow Labs, which brings deep expertise in
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critical roles of ion channels—particularly the TRP superfamily—in physiological and pathological processes. Our interdisciplinary approach spans from foundational electrophysiology to translational models
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understanding on the origin of nucleic acids that are shed in liquid biopsies, such as blood, using cancer models (mouse and rat) and patient samples of neuroblastoma disease, a rare childhood cancer. Nucleic
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drive neuroinflammation in synucleinopathies and other neurodegenerative diseases. The candidate will employ advanced in vivo models and spatial technologies to dissect the roles of tissue-resident
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systems and computational biology. Models include yeast, fly, mouse, and pluripotent human cell systems. Research groups have access to state-of-the-art research and top-notch support core facilities and