Post-Doctoral Associate

Summary: Perform research on RNA and DNA aptamers. Discover aptamers by in vitro selection for fluorescent imaging. Perform biophysical characterization of aptamers.
Job Duties:
Perform in vitro selection of nucleic acids (40%)
-Selection of functional nucleic acids (DNA and RNA) by SELEX
-Prepare and submit NGS of SELEX libraries
-NGS analysis
Biophysical characterization of RNAs (40%)
-Characterize functional nucleic acid binding to target ligands
-Characterize functional behavior (fluorescence, catalysis) of nucleic acids
Routine operational lab duties (20%)
-Preparation of buffers, stock solutions, etc as needed for above tasks

Required Qualifications:
PhD in biochemistry
5+ years of experience with in vitro selection of fluorescent aptamers
5+ years of experience with biophysical nucleic acids assays
5+ years of experience with optical spectroscopy (UV-vis, fluorescence)

The department of Biochemistry, Molecular Biology and Biophysics is committed to understanding the molecular mechanisms of metabolic diseases and cancer; developing novel strategies in biocatalysis and biotechnology; and advancing knowledge through structural biology and molecular biophysics.   We organize ourselves into research divisions with emphasis on Chemical and Structural Biology , Metabolic and Systems Biology , Molecular Biology and Synthetic Biology and Biotechnology . We are housed in new buildings with state-of-the-art research and support facilities.

Pay Range: $61,008 or new NIH minimum when announced; depending on education/qualifications/experience

Please visit the Benefits for Postdoctoral Candidates website for more information regarding benefit eligibility.

• Competitive wages, paid holidays, and generous time off
• Continuous learning opportunities through professional training
• Medical, dental, and pharmacy plans
• Healthcare and dependent care flexible spending accounts
• University HSA contributions
• Disability and life insurance
• Employee wellbeing program
• Financial counseling services
• Employee Assistance Program with eight sessions of counseling at no cost

Applications must be submitted online.  To be considered for this position, please click the Apply button and follow the instructions.  You will be given the opportunity to complete an online application for the position and attach a cover letter and resume.

Additional documents may be attached after application by accessing your "My Job Applications" page and uploading documents in the "My Cover Letters and Attachments" section.

To request an accommodation during the application process, please e-mail employ@umn.edu or call (612) 624-8647.

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