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Details
Posted: 17-Apr-25
Location: Chapel Hill, North Carolina
Categories:
Academic/Faculty
Medical - Research
Internal Number: 298271
Vacancy ID: PDS004483
Position Summary/Description:
A postdoctoral research associate position is available in the laboratory of Chrystal Starbird in the Department of Biochemistry and Biophysics at UNC Chapel Hill. The Starbird lab is broadly focused on understanding the molecular basis of disease, utilizing structural, biochemical and biophysical studies to investigate transmembrane proteins that are involved in phagocytic pathways, including ABC transporters and TAM receptors, which is our current major focus. TAM receptors are a clinically important and mechanistically under-studied RTK subfamily that play a vital role in maintaining cellular homeostasis through the clearance of apoptotic cells and control of inflammatory and immune responses. While it has been shown that viruses can hijack this TAM receptor clearance function to enter host cells though a form of 'apoptotic mimicry,' the mechanisms that drive this process have not been well studied. This position will focus initially on investigating the role of TAM receptor tyrosine kinases in viral spread. In collaborative work with another UNC-based lab, this project will aim to utilize a very wide variety of techniques from single-cell assays to protein structure determination.
Education and Experience:
Experience in basic biochemical and biophysical techniques, including structural biology and/or imaging, is preferred, but not required, as is experience in molecular studies of virus entry.
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About The University of North Carolina at Chapel Hill
Carolina rates among the nation’s great institutions of higher education, set on an historic and beautiful campus that celebrates all four seasons. Carolina’s students, faculty and staff come here from around the world, bringing varied cultural, racial and ethnic heritages that help make UNC-Chapel Hill a thriving intellectual center. We’re repeatedly ranked the nation’s best value in higher education for students seeking to earn a college degree – the University has garnered the top spot each time since the ranking’s launch in 1998.Whether you’ve just started your career, are new to academia or are a seasoned professional with assorted campus experiences to draw on, we hope you will find a great place at Carolina.
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