Post-Doc Research Associate-Starbird Lab

Updated: 3 months ago
Location: Chapel Hill, NORTH CAROLINA

Details

Posted: Unknown

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Summary:

Summary here.



Details

Posted: 17-Apr-25

Location: Chapel Hill, North Carolina

Categories:


Academic/Faculty
Medical - Research

Internal Number: 298271


Vacancy ID: PDS004483

Position Summary/Description:


A postdoctoral research associate position is available in the laboratory of Chrystal Starbird in the Department of Biochemistry and Biophysics at UNC Chapel Hill. The Starbird lab is broadly focused on understanding the molecular basis of disease, utilizing structural, biochemical and biophysical studies to investigate transmembrane proteins that are involved in phagocytic pathways, including ABC transporters and TAM receptors, which is our current major focus. TAM receptors are a clinically important and mechanistically under-studied RTK subfamily that play a vital role in maintaining cellular homeostasis through the clearance of apoptotic cells and control of inflammatory and immune responses. While it has been shown that viruses can hijack this TAM receptor clearance function to enter host cells though a form of 'apoptotic mimicry,' the mechanisms that drive this process have not been well studied. This position will focus initially on investigating the role of TAM receptor tyrosine kinases in viral spread. In collaborative work with another UNC-based lab, this project will aim to utilize a very wide variety of techniques from single-cell assays to protein structure determination.

Education and Experience:


Experience in basic biochemical and biophysical techniques, including structural biology and/or imaging, is preferred, but not required, as is experience in molecular studies of virus entry.


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