Research Assistant in Cardiovascular Development and Regeneration

Fixed term for 12 months, full-time

About us:

At the  Department of Physiology Anatomy & Genetics (DPAG)  we undertake discovery science where we reassemble physiological processes at the molecular, cellular, tissue and systems level of organisation. In so doing we provide a bridge to translational medicine, and interface between physical and life sciences. We are committed not only to innovative research and the highest standard of teaching, but also to creating an inclusive and supportive working environment.

Overview of the role:

We are seeking a Research Assistant to join the Simões Group. The ideal candidate will be a highly motivated scientist with hands-on laboratory experience in molecular biology and cell culture techniques, strong organisational skills and the ability to work both independently and as part of a multidisciplinary team. In this role, you will be responsible for supporting cutting-edge research in cardiovascular development and regeneration, including laboratory maintenance, zebrafish husbandry management, molecular biology experiments and cell culture work. This post is available from October 2025 at the earliest and is fixed term for 12 months from the start date.

Flexible working:

While this is a full-time role, we welcome applications from individuals who wish to be considered for part-time working or other flexible working arrangements, subject to operational requirements.  

Key responsibilities:

• Maintain laboratory organisation, stock control and ensure compliance with safety and quality standards
• Manage zebrafish breeding colonies and conduct experimental procedures according to Home Office regulations
• Perform routine molecular biology techniques and prepare samples for downstream analyses such as flow cytometry, immunofluorescence and sequencing
• Conduct 2D and 3D cell culture techniques, including maintenance and optimisation of culture conditions
• Assist with advanced techniques including CRISPR/Cas9 genome editing and single-cell approaches
• Contribute to project planning, data analysis and preparation of scientific reports and presentations
• Train new staff and students as required

Selection criteria:

• Hold a first degree in biological sciences, biomedical sciences or related field, with demonstrable understanding of developmental, cell and molecular biology principles
• Previous hands-on laboratory experience in molecular biology techniques and/or cell culture techniques
• Strong organisational abilities to support laboratory operations
• Self-motivated with ability to work independently, while collaborating effectively as part of a team
• Excellent written and verbal communication skills, including ability to maintain detailed records and present data clearly
• Ability to adapt to changing experimental demands and learn new techniques with exceptional attention to detail
• Previous experience working with zebrafish models (desirable)
• Experience with human pluripotent stem cells (hPSCs) or organoid culture systems (desirable)

What we offer:

Your wellbeing at work matters, so we offer a range of family friendly and financial benefits.

 Interviews are likely to take place during the week commencing 11th August and will be face to face or held on Microsoft Teams, depending on availability of the candidates.

Applications are particularly welcome from women, black and minority ethnic candidates who are under-represented in academic posts in Oxford.

We also welcome applications from individuals who would like to pursue a DPhil after completion of this contract.