We offer a postdoc position in a project aiming at the development of organoid models for inflammatory bowel diseases. The project is a collaboration between the Fraunhofer Institute for Translational Medicine and Pharmacology ITMP, the Medical Campus of the Goethe University, and Sanofi. The position will be based in Frankfurt am Main.
What you will do
- Development of patient-derived organoid models for inflammatory bowel diseases using primary cells from biopsy samples. Innovative development of complex co-culture systems combining patient-derived organoids with autologous immune cells to recreate human intestinal inflammation, establishing a novel pharmacological platform for preclinical drug evaluation.
Evaluate disease trajectory and predictive potential through comparative spatial transcriptomic and single-cell analysis of organoid models and patient biopsy samples.
What you bring to the table
- PhD in biology, biochemistry, molecular biology, cell biology, immunology, or related discipline
- Experience with stem cell-derived organoid culture, profound knowledge of molecular, cell biology and immunology techniques with hands-on experience
- Advantageous but not required: Expertise in single cell analysis technology3D high-throughput imaging or patient biosample processing
- Ability to work in a multidisciplinary and international team of scientists with excellent written and oral communication skills
- Independent problem solving and systematic data-driven experimental design and execution
- Fluent in English, German is a plus
What you can expect
- A multidisciplinary project with a strong focus on applied science
- Close collaboration with clinical researchers and a pharmaceutical industry partner
- Opportunities to present and publish your findings
- High degree of independence and autonomy
- Support for continuing education and further qualification
The weekly working time is 39 hours. This position isinitially limited to two years and is also available on a part-time basis. We value and promote the diversity of our employees' skills and therefore welcome all applications - regardless of age, gender, nationality, ethnic and social origin, religion, ideology, disability, sexual orientation and identity. Severely disabled persons are given preference in the event of equal suitability. Appointment, remuneration and social security benefits based on the public-sector collective wage agreement (TVöD). Additionally Fraunhofer may grant performance-based variable remuneration components.
With its focus on developing key technologies that are vital for the future and enabling the commercial utilization of this work by business and industry, Fraunhofer plays a central role in the innovation process. As a pioneer and catalyst for groundbreaking developments and scientific excellence, Fraunhofer helps shape society now and in the future.
Interested? Apply online now. We look forward to getting to know you!
In case of any further questions, please do not hesitate to contact:
Prof. Dr. Aimo Kannt, e-mail: aimo.kannt@itmp.fraunhofer.de
Fraunhofer Institute for Translational Medicine and Pharmacology ITMP
www.itmp.fraunhofer.de
Requisition Number: 80552 Application Deadline:
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