Lab assistant (student worker) for Genotyping of O-GlcNAc Related Disease Models

The Daan van Aalten laboratory at the Department of Molecular Biology and Genetics at Aarhus University is looking for a lab assistant (student worker) for genotyping of O-GlcNAc related disease models.

Expected start date and duration of employment
This is a fixed term position from the 1st of September 2025 until end of June 2026.

Job description

• You will be contributing to experiments investigating the role of O-GlcNAcylation in neurological disease models.
• You will be working primarily with OGT- and OGA-mutant mouse tissues.
• The position will focus on aspects of tissue dissection, sample preparation, and basic molecular biology workflows specific to glycosylation biology.
• You will be involved in the day-to-day running of experiments, including genotyping, reagent prep, and data documentation.
• These activities will be in close collaboration with postdocs and PhD students in the lab, as well as external collaborators focusing on O-GlcNAc-specific mass spectrometry and sequencing.

• Practical experience genotyping CRISPR-edited mouse lines with mutations in Ogt and/or Oga.
• Proven ability to handle and process neural tissues from O-GlcNAc-related disease models, including embryonic and adult brain samples.
• Experience with immunostaining and western blotting using O-GlcNAc-specific antibodies, including RL2 and CTD110.6.
• Experience with molecular biology techniques tailored for glycosylation-sensitive samples, especially RNA extraction.
• Hands-on involvement in preparing samples for mass spectrometry.
• Accurate record-keeping and ability to follow complex genotyping schemes for transgenic mouse colonies.
• Documented contribution to research projects focused on O-GlcNAc-dependent transcriptional or neurological processes.

The lab assistant will be affiliated to the Department of Molecular Biology and Genetics.

The Department of Molecular Biology and Genetics is part of the Faculty of Natural Sciences, Aarhus University and comprises research within the areas of Plant Molecular Biology, Neurobiology, RNA Biology and Innovation, Protein Science, Cellular Health, Intervention and Nutrition. There are currently 75 full time scientific staff and 95 PhD students. The department is responsible for two educations: Molecular Biology and Molecular Medicine with a yearly uptake of 160 students in total.

Please refer to http://mbg.au.dk/  for further information about The Department of Molecular Biology and Genetics and to https://nat.au.dk/  and http://www.au.dk/  for information on Faculty of Natural Sciences and Aarhus University, respectively.

Place of work and area of employment
The place of work is at Universitetsbyen 81, 8000 Aarhus C, and the area of employment is Aarhus University with affiliated institutions.

Contact information
For further information, please contact: Professor, Daan van Aalten, daan@mbg.au.dk

Formalities and salary range

Salary and terms as agreed between the Danish Ministry of Taxation and the Confederation of Professional Unions.

Aarhus University’s ambition is to be an attractive and inspiring workplace for all and to foster a culture in which each individual has opportunities to thrive, achieve and develop. We view equality and diversity as assets, and we welcome all applicants.

The application must be submitted via Aarhus University’s recruitment system, which can be accessed under the job advertisement on Aarhus University's website.