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immunity. However, the detailed interactions between involved vs bystander cells and the resulting activation and induction of type 2 immune responses are incompletely understood. Thus, treatment approaches
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: Protein-protein interactions (PPIs) are important mediators of most cellular processes. Understanding how proteins interact with each other, ideally at structural resolution, is key in understanding
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the molecular mechanisms modulating genome maintenance pathways in the cell. The Beli group has expertise in quantitative proteomics approaches in analyzing protein interactions and regulation on chromatin
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characterized by distinct phenotypic and functional properties, as well as distinct activation and interaction potentials and localization. Thus, type 1 dendritic cells are known to cross-present antigens and
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application platform. Qualification profile: Are you an ambitious scientist looking to push the boundaries of research while interacting with colleagues from multiple disciplines and cultures? Then joining
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to push the boundaries of research while interacting with colleagues from multiple disciplines and cultures? Then joining the IPP is your opportunity to give your scientific career a flying start! All you
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molecular mechanisms for altered interaction that affects HSC output in aging. This will be achieved via the implementation of state of the art multicolor flow cytometry analyses, imaging, omics techniques (e
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. Specific areas include the theoretical and experimental aspects of quantum materials and atomically resolved dynamics, fundamental light-matter interaction, accelerator-based light sources, coherent
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polyubiquitylation of relevant cellular proteins in a controlled and linkage-selective manner, as well as b) identify selectively modified substrates, the responsible enzymes and linkage-selective interaction partners
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particular, I found that a P-body protein directly interacts with a translation initiation factor, suggesting the existence of a novel molecular “switch” capable of activating dormant mRNAs. Our lab combines