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niches. Building on our experience in cell-fate tracking tracking and studying various stages of the metastatic cascade, we set out to follow tumour cell-niche interactions to reveal how distant sites
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: Design and perform experiments using NMR spectroscopy and single-molecule FRET Purify and biochemically characterize proteins and their complexes Analyze and interpret advanced biophysical and single
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in solution for up to hours. Now, we leverage the unique abilities of nanopore trapping to detect proteins and their conformations, dynamics, interactions, catalytic mechanisms etc. in real-time
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this project, you will: Design and perform experiments using NMR spectroscopy and single-molecule FRET Purify and biochemically characterize proteins and their complexes Analyze and interpret advanced
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: design and operation of scanning probe instrumentation fabrication of van der Waals heterostructures transport, optical spectroscopy, and quantum sensing experiments data analysis, modeling, and scientific
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DyeCycling to map protein energy landscapes in unprecedented detail, thereby gaining access to previously overlooked effects, like dynamic disorder, with far-ranging consequences for the design and functional