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threats, using in vitro exposure-response assays, RNA and whole-genome sequencing, PK/PD modeling, and high-resolution microscopy. This interdisciplinary approach challenges current resistance paradigms
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, immunoprecipitation, and basic chromatin assays (e.g., ChIP). • Support viral vector preparation and use (e.g., lentivirus or AAV) for in vitro and in vivo genetic manipulation under supervision. • Assist with
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University of North Carolina at Chapel Hill | Chapel Hill, North Carolina | United States | 2 months ago
in vitro experiments to study novel combination therapies in breast cancer mouse models, organoids, and primary mammary epithelial cell culture. Additional responsibilities will include management
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Institute of Animal Reproduction and Food Research of Polish Academy of Sciences | Poland | 3 months ago
Responsibilities • Isolation of CD34⁺ hematopoietic stem and progenitor cells from cord blood donors for in vitro studies. • Preparation of RNA and chromatin libraries for NGS (RNA-seq, ATAC-seq, ChIPmentation
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(direct and indirect pathway neurons) in mouse models of HD, and to dissect the regulatory role of m6A RNA methylation in these processes. The project will combine in vivo and in vitro approaches, advanced
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networks (PMID:26655834, PMID:34106209, PMID:39009834 and BioRxiv. https://doi.org/10.64898/2025.12.01.691495). The importance of Arp2/3 complex subunit isoforms is evident from the observation that loss
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experiments. Generation of lentiviral vector for in vivo or in vitro gene delivery; primary neuronal culture; human fibroblast and pluripotent stem cell culture. Compile and analyze data with appropriate
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, optogenetics, genome engineering, induced pluripotent stem cell differentiation to neurons/organoids, and in vitro and in vivo electrophysiological measurements. Our long-term scientific goal is to dissect
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analyze samples by PCR and qPCR. Cultures mammalian cell lines (e.g. murine, human, etc.) and conducting cell-based in vitro assays. Operates lab equipment such as centrifuges, pH meters, analytical
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vitro assays. Orders laboratory supplies and maintains a database of supply inventory. Responsible for packing, unpacking, storing and classification of lab supplies and specimens (mouse and human