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analyses in clinically relevant human tumor models. In the first part, the student will define the plecstatin binding site on the plectin molecule. This will involve in vitro expression and purification
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clonal development. To study these processes, advanced experimental models will be used, including genetically modified animals, iPSC-derived hematopoietic cells, 3D organoids, and in vitro HSC culture
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whole-body physiology levels. We utilize a variety of in vitro (cell) models and mouse models to investigate specific transcription factors, gene and protein regulatory pathways, and metabolic changes in
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genomics, transcriptomics, and epigenomics with mechanistic studies using in vitro and in vivo models to dissect B-ALL and related hematologic malignancies. The lab also studies normal hematopoietic stem
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-forming DNA/RNA sequences to investigate their structural equilibrium, dynamics, and ligand binding interactome in vitro and in the intracellular space. The outcome will provide fundamental insights
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programme in all activities related to in vitro production and preservation of horse embryos (oocyte recovery, oocyte maturation, sperm preparation and intracytoplasmic sperm injection, embryo culture, embryo
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Chemistry or a related discipline. Good knowledge of English, both verbal and written. Knowledge of synthetic techniques and willingness to learn and perform chemical biology experiments at the in vitro level
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hydrogels; preparation of micro and/or nanoparticles; in vitro cell culture; differentiation of stem cells into cardiomyocytes. Requirement for granting the fellowship: The applicants may apply without prior
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, reproduction, and development. They use cutting-edge single-cell, spatial, in vitro, and surgical approaches in multiple model species and in human organoids to investigate the uterine endometrium and maternal
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Umeå Plant Science Centre (UPSC, https://www.upsc.se ) which is a centre of excellence for experimental plant research and forest biotechnology in Northern Sweden. Our mission is to perform excellent and