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modalities) allow clinically relevant readouts in both small and large animal models. Tasks and responsibilities You will use in vitro assays and small- and large-animal models to unravel how the innate
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electrophysiological approaches (in vivo or in vitro) is required. Demonstrated ability to assess neurobiology of cardiorespiratory neurons and their function. Familiarity with disease models of opioid-induced
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the cellular, thrombus, and organ levels? Would you like to be part of a prestigious doctoral network working to revolutionize personalized medicine by using cutting-edge in silico, in vitro, and in vivo
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-edge in silico, in vitro, and in vivo technologies to understand, predict and treat thrombosis? This is your chance!! Our goal: Develop multi-level thrombosis risk prediction models by integrating
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, pharmacology, molecular biology, or related field). Responsibilities: Lead translational drug development studies using patient-derived in vitro and in vivo cancer models, including orthotopic xenograft systems
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therapeutics using in vitro methods, validate them in a mouse model of MS, and decipher their mechanisms of action. In addition to performing experiments, you will develop new directions for the project, train
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, pharmaceutics, or a related field. The candidate must be highly motivated with evidence of productivity from peer-reviewed publications and scientific presentations. Candidates skilled in in vitro and in vivo
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malignant transformation under chronic inflammation. Using in vitro systems and murine models of aging and chronic inflammation, we will perform integrated transcriptomic and metabolic analyses to dissect
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these questions, we will combine in vitro culture systems with in vivo murine models of infection, complemented by transcriptomic and metabolic profiling approaches. This integrative strategy will allow us to
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analyses in clinically relevant human tumor models. In the first part, the student will define the plecstatin binding site on the plectin molecule. This will involve in vitro expression and purification