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Institut de Psychiatrie et Neurosciences de Paris (IPNP) | Paris 15, le de France | France | 2 months ago
membrane-proximal (pTM) and cytosolic (Cyto) domains (Fig. 1). We have recently found that FP1 mediates membrane fusion in vitro and that the presence of cholesterol and ceramide in the membrane strongly
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., 2022. Calibrated Photoacoustic Spectrometer Based on a Conventional Imaging System for In Vitro Characterization of Contrast Agents. Sensors 22, 6543. https://doi.org/10.3390/s22176543 Nicolas-Boluda, A
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these digestive processes. To this end, in vitro digestion models and in vivo animal studies are used in a complementary manner to obtain both mechanistic insights and physiologically relevant responses. A central
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stress, e.g. through mechanical agitation or by applying shear forces in microfluidic devices, and will investigate how this impacts phase separation and aggregation of TDP-43, FUS or TAF15 in vitro. We
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in the development of glioblastomas. The postdoc will use in vitro approaches to culture patient-derived cells with oligodendrocytes and will also be required to carry out or assist with in vivo
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the characterization of biological activities of novel anticancer compounds, including metal complexes and/or metal-binding agents, in two- and three-dimensional in-vitro models. Strong expertise and state-of-the-art
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vitro human cell cultures and cell-based models for simulating the oral cavity. Hands-on experience on (ultra) high-performance liquid chromatography, SDS-PAGE, UV-Vis and fluorescence spectroscopy
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to meet project needs, integrating their work with existing in vitro and in vivo data to support consumer chemical safety assessments across multiple P&G businesses. Essential Functions This research will
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lead the development of new in vivo and in vitro technologies, including a mouse model of endometriosis in which endometrial tissue from patients is transplanted into the abdominal cavity
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that the toxin induces DNA damage responses in cultured cells that activates a senescence tumour suppressor mechanism (https://doi.org/10.1038/s41467-019-12064-1). Cells undergoing toxin-induced senescence undergo