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in identifying new targets through synthetic lethal interactions with AR signalling inhibitors and other approved drugs using CRISPR/Cas screening s in vitro and in vivo. About the role The candidate
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National Institutes of Natural Sciences, National Institute for Physiological Sciences | Japan | 10 days ago
optical imaging; In vitro electrophysiology; Large-scale data analysis; Mathematical modeling. We prioritize candidates who are already proficient and have abundant experience in some of these technologies
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mechanical behaviors of condensates, both in vitro and in living cells. The successful candidate will lead optical tweezer microrheology experiments to quantify the viscoelastic properties and phase
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in vitro models. The main aim is to deepen the understanding of pregnancy complications, with the goal of identifying underlying mechanisms and contributing to the development of new diagnostic and
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Requirements: Candidates meeting the following criteria can enter the competition: scientific achievements and requirements for the position applicable at Wroclaw Medical University (vide: http://www.umw.edu.pl
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Requirements: Candidates meeting the following criteria can enter the competition: scientific achievements and requirements for the position applicable at Wroclaw Medical University (vide: http://www.umw.edu.pl
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electrophysiology. Experience working with rodent model and human primary sensory neurons, in vitro. Familiarity with calcium channels and their role in neuronal function is highly desirable but not required. Strong
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on recent findings on the essential target enzymes DOI: 10.1021/acs.jmedchem.5c00865. Project role includes purification of recombinant enzymes and screening inhibitors in vitro. Ideal candidates will have
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) datasets derived from extracellular vesicles and tissues from in vitro and in vivo models. Integrate multi-omics datasets to uncover molecular pathways and networks underlying disease mechanisms. Curate and
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genomics, transcriptomics, and epigenomics with mechanistic studies using in vitro and in vivo models to dissect B-ALL and related hematologic malignancies. The lab also studies normal hematopoietic stem