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immunity and prevent pulmonary diseases. The research will use both in vitro (air-liquid interface cultures, organoids, and organ-on-a-chip) and in vivo (transgenic and knockout mice) model systems
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physiologie et la virulence du bacile seront caractérisées en combinant différentes approches. Des bio-essais in vitro seront réalisés pour étudier l'interaction du métabolisme secondaire bactérien sur les
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-PCR/RT-qPCR, and general bacterial genetics techniques. The use of microfluidic devices to analyze gene expression in in vitro grown biofilm communities. Identifying components of innate immunity and
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, in vitro mammalian cell culture, and aerobic and anaerobic bacterial culture. They will also help with animal experiments (mice) and manage the mouse colony, along with recruitment of patients
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a combination in vitro biophysical measurements, high resolution x-ray crystallographic analyses, electron cryo microscopy (cryoEM), and cell-based fluidics studies. The group has access to a range of
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scientists and clinicians from across the School and King’s College London. More information: https://www.kcl.ac.uk/scmms About The Role Applications are invited for a talented and enthusiastic postdoctoral
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are: Conducting in vitro and in vivo experiments with medulloblastoma models within the parameters of the funded project, under the supervision of the lead researcher. Collaboration in experimental design, as
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for the analysis of transcriptomic (snRNA-Seq, total RNA-Seq, microRNA-Seq) and epigenetic (CUT&Tag, ATAC-Seq) datasets derived from extracellular vesicles and tissues from in vitro and in vivo Integrate multi-omics
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the effects of various drugs or genetic modifications on cell culture growth, survival, migration and invasion in vitro and tumor growth in vivo • Perform DNA, RNA and protein analysis using PCR, RT-PCR
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. More information on our research can be found on our lab webpage https://www.browne-lab.org/ . Please contact Dr. Hilary Browne hilary.browne@ucc.ie for informal enquiries. The primary role is to