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to Westlake University Homepage: https://en.westlake.edu.cn/ Link to School of Engineering Homepage: https://en-soe.westlake.edu.cn/ Department of Electronic and Information Engineering Electronic and
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of phosphoinositide 3-kinase (PI3K) signaling in allergy, metabolic control, obesity, diabetes and cancer; see https://p3.snf.ch/project-189065 ii) developing and validation of novel chemical probes and degraders
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threats, using in vitro exposure-response assays, RNA and whole-genome sequencing, PK/PD modeling, and high-resolution microscopy. This interdisciplinary approach challenges current resistance paradigms
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, and the immune microenvironment. Treatments will be tested in combination with a range of standard of care chemotherapies and immunotherapies. This work involves both in vitro (cell culture) and in vivo
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, optogenetics, genome engineering, induced pluripotent stem cell differentiation to neurons/organoids, and in vitro and in vivo electrophysiological measurements. Our long-term scientific goal is to dissect
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ultimately reversed or rebuilt using bioengineering and synthetic biology approaches. The successful candidate will: Investigate mechanisms of T-cell development, aging, and thymic involution using in vitro
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, optogenetics, genome engineering, induced pluripotent stem cell differentiation to neurons/organoids, and in vitro and in vivo electrophysiological measurements. Our long-term scientific goal is to dissect
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characterization of the chip in a cleanroom environment In vitro cell culture of inflammatory cells development of an on-chip imaging technique Collaborations. This project is in collaboration between two different
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penumbra — the zone of partially injured but potentially recoverable neurons surrounding a brain infarct. Using advanced in-vitro models, we study how metabolic stress affects neuronal network function and
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embedded within the Groningen Research Institute of Pharmacy (GRIP), Department of Pharmaceutical Technology and Biopharmacy (PTB, https://www.rug.nl/research/pharmaceutical-technology-and-biopharmacy