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in vitro functional assays to characterize the effects of metabolic modifications on osteoclast differentiation and functions, particularly their immune function. - To actively collaborate with all
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the experimental procedures; performing animal experiments using mouse models of HIV/AIDS and data analysis, Work under general supervision to: perform in vitro cell culture experiments, including experiments using
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studies innate immunity to Zika virus infection using a combination of in vitro, in vivo, and computational approaches. We need additional research support carrying out experiments and analyzing data
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the regulation of ATP13A2 in lysosomes remains unclear. This project will explore the mechanism by which ATP13A2 is regulated by co-factors such as lipids and proteins i) in vitro on purified ATP13A2 protein and
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into complex tissue-like structures. These structures offer exciting opportunities to mimic organ development and embryogenesis in vitro. However, current organoid models still only partially replicate natural
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experience in toxicology (min. 3 years) and a solid understanding of toxicological principles and best practices (PhD degree, ERT or DABT certification are a plus) Knowledge of in vitro toxicology, New
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learning-based approaches to advanced molecular design Network Pharmacology Quantum computing Hybrid In Silico/In Vitro Pipelines Work at the interface of medicinal chemistry and computational approaches
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for Human Genetics in Oxford. The Tzima research group investigates the role of mechanotransduction in cardiovascular disease and the laboratory is at the cutting edge of developments in in vitro and in vivo
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vivo imaging platforms. Key responsibilities To work within the Mansour and Roghanian labs, and with collaborators at Southampton and beyond. To design, conduct, and analyse in vitro and in vivo
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, drug discovery, other therapeutic interventions, and/or vaccine development. Research programs can also span any area of in vitro , in vivo , and/or in silico investigation. PHRI and the Center