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Field
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processing in the mammalian cochlea in vivo , and how these influence central auditory neuronal pathways. The project will primarily involve using in vivo 2-photon imaging and AAV-gene delivery applied to a
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of collegiality Desirable criteria Extensive experience with confocal microscopy and live imaging Experience with biomechanics concepts and techniques such as AFM, micropipette aspiration and/or nanoindentation
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on autofluorescence (AF) imaging and Raman spectroscopy for detection of metastatic lymph nodes during breast cancer surgery. Engaging with and reporting to Dr Alexey A. Koloydenko (Department of
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experience with confocal microscopy and live imaging Experience with biomechanics concepts and techniques such as AFM, micropipette aspiration and/or nanoindentation Current Home Office Personal Licence
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fluorescence-lifetime detection (Fast-FLIM) and temporal focusing. This instrument will deliver quantitative, sub-second imaging of live three-dimensional cell-culture and organoid models, advancing fundamental
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or orthotopic tumour models Supporting preclinical treatment studies involving standard-of-care or experimental agents Applying in vivo imaging techniques (e.g., bioluminescence imaging) to monitor tumour
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using a range of methods including cutting-edge single cell and imaging techniques. Ultimately this information will provide fundamental insights into human biology and may in the future lead to improved
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developing and applying deep learning models, particularly in areas such as natural language processing (e.g. use of LLMs), computer vision (e.g. CNNs for image classification), and multimodal data integration
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in sustainability, photonic and quantum technologies, new nanostructured materials, sensing, imaging and clean energy. The group adopts an interdisciplinary approach to provide leading-edge research in
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and assessment of ocular inflammation models, such as intravitreal injections, ocular imaging techniques and flow cytometry. Moreover, applicants will perform a variety of additional procedures such as